All published articles of this journal are available on ScienceDirect.

REVIEW ARTICLE

A Review and Experimental Analysis of Denoising Techniques for Medical Images

The Open Neuroimaging Journal 26 Sept 2025 REVIEW ARTICLE DOI: 10.2174/0118744400404813250924064413

Abstract

Introduction

Magnetic Resonance Imaging (MRI) and High-Resolution Computed Tomography (HRCT) are crucial for comprehensive diagnosis and treatment planning, as they provide detailed anatomical information. However, noise introduced during image acquisition often degrades the quality of these images, obscuring key anatomical features and complicating accurate diagnoses.

Methods

This study compared the performance of eight denoising algorithms: BM3D, EPLL, FoE, WNNM, Bilateral, Guided, NLM, and DnCNN. Both objective metrics, including Mean Squared Error (MSE), Structural Similarity Index (SSIM), and Peak Signal-to-Noise Ratio (PSNR), as well as perceptual quality metrics, such as NIQE, BRISQUE, and PIQE, were employed to assess their effectiveness.

Results

BM3D consistently outperformed other algorithms at low and moderate noise levels, achieving the highest PSNR and SSIM values while preserving structural integrity and perceptual quality. For high noise levels, conventional algorithms, such as EPLL and WNNM, demonstrated competitive performance in homogeneous areas, preserving fine texture, but were limited by computational complexity.

Discussion

One of the challenges in image denoising is preserving the finer detail structures of images while efficiently removing noise. Finding a balance between the reduction of noise and preservation of image integrity can be a lifesaving challenge, especially in cases where the images are in high detail, such as in the medical world.

Conclusion

This study highlights the trade-offs between denoising quality and computational efficiency among various algorithms for MRI and HRCT images. While BM3D remains a dependable choice for moderate noise levels, advanced deep learning-based methods, such as DnCNN, are better suited for handling significant noise variations without compromising critical diagnostic features.

Keywords: MRI, HRCT, Denoising, Noise variance, Image processing, Healthcare.
Fulltext HTML PDF
1800
1801
1802
1803
1804