Primary Intracranial Choriocarcinoma Located in the Suprasellar Region

Xiuli Li1, 2, #, Kazuhiro Murayama1, #, *, Ayumi Watanabe1, Masato Abe3, Hiroshi Toyama1
1 Department of Radiology, Fujita Health University, Toyoake, Japan
2 Department of Radiology, Sichuan Cancer Hospital, Chengdu, Sichuan, China
3 Department of Pathology, School of Health Sciences, Fujita Health University, Toyoake, Japan

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© Li et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Radiology, Fujita Health University, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan; Tel: 81-562-93-9259; Fax: 81-562-95-2253; E-mail:

These authors contributed equally to this work.


A 10 year old girl was admitted to our hospital due to headache, nausea, and weight loss for about half a year. She also had visual field disorders. Suprasellar tumor was found by X-ray computed tomography, and magnetic resonance imaging showed a ring-like lobulated enhanced mass with hemorrhage and necrosis. Biopsy of this lesion showed primary intracranial choriocarcinoma on histopathological examination. The serum human chorionic gonadotropin (hCG) level was measured after the biopsy and was elevated at 71,298.2 IU/L. The patient died due to hydrocephalus caused by an increase in the size of the tumor with a larger amount of hemorrhage than the preoperative features. If young patients present with a suprasellar lobulated mass with hemorrhage, the serum hCG level should be measured before operation.

Keywords: Magnetic resonance imaging, Primary intracranial choriocarcinoma, Serum hCG, Suprasellar tumor.