Aims and Scope
Trends in DNN Model based Classification and Segmentation of Brain Tumor DetectionPooja Kataria, Ayush Dogra, Mili Gupta, Tripti Sharma and Bhawna Goyal
The Open Neuroimaging Journal, 2023; 16: e187444002303060.
Electronic Publication Date: April 06, 2023
Peak Activation Shifts in the Sensorimotor Cortex of Chronic Stroke Patients Following Robot-assisted Rehabilitation TherapyLoukas G. Astrakas, Shasha Li, Mark P. Ottensmeyer, Christian Pusatere, Michael A. Moskowitz, A. Aria Tzika
Ischemic stroke is the most common cause of complex chronic disability and the third leading cause of death worldwide. In recovering stroke patients, peak activation within the ipsilesional primary motor cortex (M1) during the performance of a simple motor task has been shown to exhibit an anterior shift in many studies and a posterior shift in other studies.
We investigated this discrepancy in chronic stroke patients who completed a robot-assisted rehabilitation therapy program.
Eight chronic stroke patients with an intact M1 and 13 Healthy Control (HC) volunteers underwent 300 functional magnetic resonance imaging (fMRI) scans while performing a grip task at different force levels with a robotic device. The patients were trained with the same robotic device over a 10-week intervention period and their progress was evaluated serially with the Fugl-Meyer and Modified Ashworth scales. Repeated measure analyses were used to assess group differences in locations of peak activity in the sensorimotor cortex (SM) and the relationship of such changes with scores on the Fugl-Meyer Upper Extremity (FM UE) scale.
Patients moving their stroke-affected hand had proportionally more peak activations in the primary motor area and fewer peak activations in the somatosensory cortex than the healthy controls (P=0.009). They also showed an anterior shift of peak activity on average of 5.3-mm (P<0.001). The shift correlated negatively with FM UE scores (P=0.002).
A stroke rehabilitation grip task with a robotic device was confirmed to be feasible during fMRI scanning and thus amenable to be used to assess plastic changes in neurological motor activity. Location of peak activity in the SM is a promising clinical neuroimaging index for the evaluation and monitoring of chronic stroke patients.
July 07, 2021
- November 25, 2020
Regional Parieto-occipital Hypoperfusion on Arterial Spin Labeling Associates with Major Depressive DisorderMarch 31, 2017
A Functional MRI-Based Model for Individual Memory Assessment in Patients Eligible for Anterior Temporal Lobe ResectionApril 27, 2017
Functional Evaluation of Awareness in Vegetative and Minimally Conscious StateMay 22, 2017
Convexity Subarachnoid Hemorrhage, Pseudomonas Aeruginosa (PA) Infective Endocarditis and Left Atrial Appendage Occluder (LAAO) Device Infection. A Case ReportMay 29, 2017
Extending Inferential Group Analysis in Type 2 Diabetic Patients with Multivariate GLM Implemented in SPM8October 24, 2017
Developing the Standard of Care for Post-Concussion Treatment: Neuroimaging-Guided Rehabilitation of Neurovascular Coupling