A Three-dimensional Deformable Brain Atlas for DBS Targeting. I. Methodology for Atlas Creation and Artifact Reduction
Atchar Sudhyadhoma, *, Michael S Okunb, Kelly D Footea, Maryam Rahmana, Frank J Bovaa
Identifiers and Pagination:Year: 2012
First Page: 92
Last Page: 98
Publisher ID: TONIJ-6-92
Article History:Received Date: 10/7/2012
Revision Received Date: 14/8/2012
Acceptance Date: 14/8/2012
Electronic publication date: 5/10/2012
Collection year: 2012
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Targeting in deep brain stimulation (DBS) relies heavily on the ability to accurately localize particular anatomic brain structures. Direct targeting of subcortical structures has been limited by the ability to visualize relevant DBS targets.
Methods and Results:
In this work, we describe the development and implementation, of a methodology utilized to create a three dimensional deformable atlas for DBS surgery. This atlas was designed to correspond to the print version of the Schaltenbrand-Bailey atlas structural contours. We employed a smoothing technique to reduce artifacts inherent in the print version.
We present the methodology used to create a three dimensional patient specific DBS atlas which may in the future be tested for clinical utility.